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- Det illustrerer at morfin brukt ved kroniske smerter ofte gir pasienten ytterligere problemer. Dette er reflektert i mange veiledere om bruk av opioider. Male kan få relativt ødelagte liv uten stor smertelindring.Utredning og behandling ved langvarig bruk og avhengighet er beskrevet i retningslinje for behandling og rehabilitering av rusmiddelp